| Date | Location | Result | |
| 11/03/21 | Milwaukee, United St | Milwaukee 2, Purdue Fort Wayne 1 | Box score |
| 10/30/21 | Fort Wayne, Ind., UN | Purdue Fort Wayne 1, IUPUI 0 | Box score |
| 10/23/21 | Green Bay, UNITED ST | Purdue Fort Wayne 0, Green Bay 0 (2OT) | Box score |
| 10/16/21 | Chicago, UNITED STAT | Purdue Fort Wayne 2, UIC 0 | Box score |
| 10/13/21 | Fort Wayne, IN, UNIT | Detroit Mercy 2, Purdue Fort Wayne 0 | Box score |
| 10/09/21 | Fort Wayne, Ind., UN | Wright St. 4, Purdue Fort Wayne 0 | Box score |
| 10/05/21 | South Bend, IN, UNIT | Notre Dame 4, Purdue Fort Wayne 0 | Box score |
| 10/02/21 | Cleveland, UNITED ST | Cleveland St. 2, Purdue Fort Wayne 1 (OT) | Box score |
| 09/25/21 | Fort Wayne, UNITED S | Purdue Fort Wayne 3, Robert Morris 1 | Box score |
| 09/18/21 | Fort Wayne, Ind., UN | Northern Ky. 1, Purdue Fort Wayne 0 | Box score |
| 09/15/21 | Kalamazoo, UNITED ST | Purdue Fort Wayne 1, Western Mich. 1 (2OT) | Box score |
| 09/11/21 | Rochester, UNITED ST | Oakland 2, Purdue Fort Wayne 0 | Box score |
| 09/05/21 | Macomb, UNITED STATE | Purdue Fort Wayne 2, Western Ill. 0 | Box score |
| 09/03/21 | Charleston, UNITED S | Purdue Fort Wayne 1, Eastern Ill. 0 | Box score |
| 08/29/21 | Fort Wayne, Ind., UN | Bellarmine 1, Purdue Fort Wayne 0 (OT) | Box score |
| 08/26/21 | DeKalb, Ill. | Northern Illinois 1, Purdue Fort Wayne 0 | Box score |