| Date | Location | Result | |
| 04/23/22 | Muncie, IN | Ball St. 3, Purdue Fort Wayne 0 (28-26,25-20,25-16) | |
| Apr 20, 2022 | Chicago, Ill. | Purdue Fort Wayne 3, Loyola Chicago 0 (32-30,25-23,27-25) | |
| 04/16/22 | Lebanon, IL | Purdue Fort Wayne 3, McKendree 1 (26-24,25-20,23-25,25-22) | |
| 04/09/22 | Fort Wayne, IN | Ball St. 3, Purdue Fort Wayne 1 (33-31,19-25,25-22,29-27) | |
| 04/07/22 | Fort Wayne, IN | Ohio St. 3, Purdue Fort Wayne 2 (25-21,20-25,26-28,27-25,15-12) | |
| 04/02/22 | Saint Charles, MO | Purdue Fort Wayne 3, Lindenwood (MO) 1 (25-15,21-25,25-23,25-17) | |
| 03/31/22 | Quincy, IL | Purdue Fort Wayne 3, Quincy 0 (25-13,25-21,25-20) | |
| 03/26/22 | Lebanon, IL | McKendree 3, Purdue Fort Wayne 1 (26-24,23-25,25-21,25-16) | |
| 03/24/22 | Fort Wayne, IN | Lewis 3, Purdue Fort Wayne 0 (25-23,25-19,25-21) | |
| 03/19/22 | Fort Wayne, IN | Loyola Chicago 3, Purdue Fort Wayne 1 (26-28,25-23,25-20,25-19) | |
| 03/17/22 | Fort Wayne, IN | Purdue Fort Wayne 3, Daemen 2 (25-20,22-25,25-21,18-25,15-8) | |
| Mar 12, 2022 | Wilberforce, Ohio | Purdue Fort Wayne 3, Central State 0 (25-17,25-22,25-20) | |
| 03/11/22 | Charleston, WV | Purdue Fort Wayne 3, Charleston (WV) 0 (25-21,25-23,25-15) | |
| Mar 04, 2022 | Chicago, Ill. | Loyola Chicago 3, Purdue Fort Wayne 0 (25-21,25-20,25-20) | |
| 02/26/22 | Fort Wayne, IN | Purdue Fort Wayne 3, McKendree 2 (25-23,25-23,25-27,24-26,15-12) | |
| 02/24/22 | Romeoville, IL | Purdue Fort Wayne 3, Lewis 0 (25-23,25-23,25-22) | |
| 02/20/22 | Columbus, OH | Ohio St. 3, Purdue Fort Wayne 0 (25-21,25-18,25-23) | |
| 02/17/22 | Muncie, IN | Ball St. 3, Purdue Fort Wayne 2 (25-21,26-28,23-25,25-20,15-6) | |
| 02/12/22 | Fort Wayne, IN | Purdue Fort Wayne 3, Quincy 0 (25-18,27-25,25-22) | |
| 02/11/22 | Fort Wayne, IN | Purdue Fort Wayne 3, Lindenwood (MO) 1 (25-13,26-24,24-26,25-18) | |
| 02/05/22 | Fairfield, CT | Purdue Fort Wayne 3, Sacred Heart 1 (25-21,25-16,24-26,25-21) | |
| Feb 05, 2022 | Cambridge, Mass. | Purdue Fort Wayne 3, Harvard 1 (25-17,20-25,26-24,25-20) | |
| 01/29/22 | Fort Wayne, IN | Saint Francis (PA) 3, Purdue Fort Wayne 2 (25-23,25-23,20-25,23-25,15-13) | |
| 01/28/22 | Fort Wayne, IN | Purdue Fort Wayne 3, Saint Francis (PA) 1 (22-25,25-21,25-21,26-24) | |
| 01/23/22 | Newark, NJ | NJIT 3, Purdue Fort Wayne 0 (25-16,25-19,26-24) | |
| 01/22/22 | Brooklyn, NY | Purdue Fort Wayne 3, St. Francis Brooklyn 1 (25-11,20-25,25-12,25-17) | |
| 01/20/22 | Fort Wayne, IN | George Mason 3, Purdue Fort Wayne 2 (18-25,20-25,25-21,25-20,16-14) | |
| 01/14/22 | Fort Wayne, IN | Purdue Fort Wayne 3, Maryville (MO) 0 (25-21,25-16,25-15) | |
| 01/08/22 | Harrogate, TN | Lincoln Memorial 3, Purdue Fort Wayne 0 (25-23,25-21,25-14) | |
| 01/07/22 | Bristol, TN | Purdue Fort Wayne 3, King (TN) 0 (25-21,25-19,25-20) |